ADAMAX 5mg Premium Research Peptide for Sale | 5mg Lyophilized Powder | ≥99% Purity | 48-Hour Delivery Across EU & UK
ADAMAX 5mg – Premium Grade
ADAMAX, offered at 5mg, is a premium-quality specialised research chemical developed for advanced scientific exploration in neuroscience. This enhanced SEMAX derivative, featuring an N-acetyl Semax base capped with an adamantyl group, is designed for increased stability in neurobiological research.
- Product Name: ADAMAX 5mg
- Catalogue Number: ADA5-024
- Molecular Formula: C22H52N16O6
- Molecular Weight: 1032.24 g/mol
- Form: Lyophilised Solid
- Also Known as: N-Acetyl Selank
Storage and Handling:
ADAMAX is supplied as a lyophilised solid to ensure maximum stability and ease of use in research environments. Store the sealed vial at -20°C, protected from light and moisture. All handling and laboratory procedures are determined by the receiving laboratory under its own protocols.
Synthesis and Quality Assurance:
ADAMAX is meticulously synthesised through a controlled process that guarantees high purity and stability, making it suitable for precise scientific studies. Our commitment to excellence ensures that each batch undergoes stringent quality control to meet the rigorous standards researchers require.
Legal and Safety Information:
UK-Peptides proudly provides ADAMAX strictly for scientific and research use. In alignment with our dedication to supporting the research community, we ensure our products meet stringent quality standards and legal requirements. Please note that our peptides, including ADAMAX, are not designed for human consumption or clinical application.
Enhance your research capabilities with ADAMAX in the EU. Explore our range of peptides designed for scientific rigour and innovation.
For researchers seeking to buy peptide online for investigations into metabolic disorders, obesity mechanisms, or lipid metabolism pathways, peptology.store offers this premium research compound with comprehensive documentation, including Certificates of Analysis and batch-specific purity data. Whether your laboratory is based in London, Berlin, Paris, or anywhere in the European Union, our guaranteed 48 hour delivery peptide service ensures your research continues without interruption.
The Scientific Foundation of ADAMAX Research
Discovery and Development
ADAMAX was developed based on the observation that the lipolytic (fat-breaking) activity of human growth hormone resides in its C-terminal region, distinct from the domain responsible for its growth-promoting effects . This discovery enabled the creation of a synthetic peptide that could be studied for its metabolic properties in isolation, potentially offering a more targeted approach to obesity research.
Early studies in obese Zucker rats demonstrated that daily oral administration of ADAMAX at 500 μg/kg body weight for 19 days reduced body weight gain by over 50% (15.8 ± 0.6 vs. 35.6 ± 0.8 g) compared to controls . Importantly, unlike chronic treatment with intact hGH, this peptide showed no adverse effect on insulin sensitivity in these animal models, as demonstrated with euglycemic clamp techniques .
Mechanism of Action: β3-Adrenergic Receptor Pathway
The primary mechanism of ADAMAX involves modulation of the beta-3 adrenergic receptor (β3-AR) pathway. A pivotal study published in Endocrinology (2001) by Heffernan and colleagues demonstrated that both hGH and ADAMAX can reduce body weight and body fat in obese mice following 14 days of chronic intraperitoneal administration.
Key mechanistic findings include:
- Increased β3-AR Expression: Both hGH and ADAMAX increase expression levels of β3-AR RNA—the major lipolytic receptor in fat cells—in obese mice, restoring them to levels comparable with those in lean mice
- β3-AR Dependence: The importance of β3-AR was verified when long-term treatment with hGH and ADAMAX in β3-AR knock-out mice failed to produce the changes in body weight and increases in lipolysis observed in wild-type controls
- Alternative Energy Pathways: In acute experiments, ADAMAX was capable of increasing energy expenditure and fat oxidation even in β3-AR knock-out mice, suggesting additional mechanisms may be involved
These findings indicate that while the lipolytic actions of ADAMAX are not mediated directly through β3-AR, the compound increases β3-AR expression, which may subsequently contribute to enhanced lipolytic sensitivity .
Effects on Lipid Metabolism
Research has demonstrated that ADAMAX influences lipid metabolism through multiple pathways:
Lipolysis Stimulation: The peptide increases lipolysis—the breakdown of triglycerides into free fatty acids and glycerol—in adipose tissue . In the 2000 study by Ng et al., adipose tissues from treated animals were found to have increased lipolytic activity compared to controls .
Lipogenesis Reduction: The peptide also reduces lipogenesis, the process of converting non-fat food materials into body fat . This dual action—increasing fat breakdown while decreasing fat formation—contributes to its overall effects on body composition.
Fat Oxidation Enhancement: Studies confirm that ADAMAX enhances fat oxidation, promoting the use of fatty acids as an energy source .
Safety and Tolerability Profile
The safety profile of ADAMAX has been evaluated in preclinical and early human studies. A randomized trial published in Regulatory Toxicology and Pharmacology found that the peptide showed good short-term tolerability and did not significantly change glucose or IGF-1 levels . Unlike full-length growth hormone, ADAMAX does not activate GH receptors and was designed to minimize negative endocrine effects .
Preclinical studies have revealed no evidence of genotoxicological or toxicological concerns, as examined in Ames tests, chromosomal aberration assays, and bone micronucleus assays . However, researchers should note that the FDA has not evaluated this peptide for safety, effectiveness, or manufacturing standards, and it is not approved for human therapeutic use .
Key Research Applications
Obesity and Weight Management Research
ADAMAX is extensively used in studies investigating body weight regulation and adipose tissue biology. Preclinical research has demonstrated:
- Significant Weight Reduction: In obese Zucker rats, the peptide reduced body weight gain by over 50% compared to controls
- Adipose Tissue Effects: Treated animals showed increased lipolytic activity in adipose tissues
- β3-AR Upregulation: The peptide increases expression of the major lipolytic receptor in fat cells
Fat Metabolism Studies
Researchers utilize ADAMAX to investigate mechanisms of lipid metabolism:
- Lipolysis Pathways: Study the breakdown of triglycerides in adipose tissue
- Lipogenesis Regulation: Investigate the formation of new fat cells
- Fat Oxidation: Explore the utilization of fatty acids for energy production
Metabolic Research
The peptide serves as a valuable tool for studying metabolic regulation without the confounding effects of full growth hormone:
- Insulin Sensitivity Studies: Unlike intact hGH, this fragment shows no adverse effects on insulin sensitivity in research models
- Energy Expenditure Research: Increases energy expenditure and fat oxidation
- β-Adrenergic Pathway Studies: Investigate the role of beta-3 adrenergic receptors in metabolic regulation
Cartilage and Tissue Repair Research
Some exploratory studies have investigated ADAMAX’s potential role in:
- Cartilage Regeneration: Preliminary research has evaluated the peptide’s effects on joint repair models
- Post-Injury Recovery: Explored for potential applications in tissue healing
- Inflammation Modulation: Studied for effects on inflammatory pathways
However, researchers should note that these applications are preliminary and based on early-phase studies .
Quality Assurance: Setting the Standard for Research Compounds
Manufacturing Excellence
peptology.store sources ADAMAX from certified GMP facilities with rigorous quality control protocols:
- HPLC Purity Analysis: ≥99% purity verified by high-performance liquid chromatography
- Mass Spectrometry Verification: Molecular weight confirmation (1815.08 g/mol) via LC-HRMS
- Batch-Specific Certificates of Analysis: Complete documentation for each production run
- Research-Use Only (RUO) Labeling: Full compliance with research compound regulations
Chemical and Product Specifications
| Specification | Detail |
|---|---|
| Product Name | ADAMAX 5mg |
| CAS Number | 221231-10-3 |
| Molecular Formula | C₇₈H₁₂₃N₂₃O₂₃S₂ |
| Molecular Weight | 1815.08 g/mol |
| Amino Acid Sequence | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe |
| Purity | ≥99% (HPLC verified) |
| Appearance | White to off-white lyophilized powder |
| Form | Lyophilized powder |
| Solubility | Soluble in sterile water, bacteriostatic water, or aqueous buffers |
| Storage (Lyophilized) | -20°C; protect from light and moisture |
| Storage (Reconstituted) | 2-8°C for short-term; aliquot and store at -20°C for longer storage |
| Shelf Life | 24 months from date of manufacture (lyophilized) |
| Intended Use | Research and laboratory use only |
| Documentation | Certificate of Analysis provided with each batch |
The Scientific Foundation of ADAMAX Research
Discovery and Development
ADAMAX is a research compound investigated for its potential biological activity and molecular interactions. Research into ADAMAX has focused on characterizing its structure, activity, and potential applications in experimental models.
Mechanism of Action
The primary mechanism of ADAMAX remains an area of ongoing research. Experimental studies investigate its molecular targets, cellular signaling pathways, and downstream biological effects.
Key areas of investigation include:
- Molecular Interactions: Study interactions between ADAMAX and relevant cellular targets
- Cellular Signaling: Investigate downstream signaling pathways activated or modulated by the compound
- Biological Activity: Characterize physiological and cellular responses in experimental models
- Mechanistic Studies: Explore potential pathways involved in observed experimental effects
Effects on Cellular and Molecular Research
Research involving ADAMAX may investigate its effects through multiple experimental pathways:
Cellular Activity: The compound can be evaluated in controlled laboratory systems to characterize cellular responses.
Molecular Signaling: Researchers can investigate changes in signaling pathways and molecular markers following experimental exposure.
Pathway Regulation: Studies may examine whether ADAMAX influences specific biochemical or cellular pathways.
Key Research Applications
Molecular Biology Research
ADAMAX can be investigated in studies examining molecular interactions and cellular signaling mechanisms.
Cellular Research
Researchers may utilize ADAMAX to investigate cellular responses, pathway regulation, and molecular activity in controlled experimental models.
Biochemical Research
The compound may serve as a research tool for characterizing biochemical interactions and mechanisms of action.
Experimental Pharmacology
ADAMAX can be investigated in experimental pharmacology models to better understand its biological properties and molecular interactions.
Quality Assurance: Setting the Standard for Research Compounds
Manufacturing Excellence
peptology.store sources ADAMAX from certified GMP facilities with rigorous quality control protocols:
- HPLC Purity Analysis: ≥99% purity verified by high-performance liquid chromatography
- Mass Spectrometry Verification: Molecular weight confirmation via LC-HRMS
- Batch-Specific Certificates of Analysis: Complete documentation for each production run
- Research-Use Only (RUO) Labeling: Full compliance with research compound regulations
Q: Is ADAMAX 5mg legal to purchase for research in the UK and EU?
A: The peptide is not approved for human use by the MHRA in the UK or the EMA in the EU . It is sold strictly for research purposes only. The sale of unlicensed peptides under “research use only” labeling is permissible for legitimate research purposes when supplied to qualified buyers such as laboratories and research facilities.
Q: Do you ship ADAMAX 5mg to EU countries?
A: Yes. As a dedicated peptide supplier, we ship to all European Union member states with our guaranteed 48 hour delivery peptide service. Our EU fulfilment centre ensures rapid delivery without customs delays. All shipments use protective packaging to maintain compound integrity during transit.
Q: What documentation do you provide with orders?
A: Every order includes a Certificate of Analysis (COA) with batch-specific purity data . Additional documentation, including HPLC chromatograms and mass spectrometry data, is available upon request for researchers requiring comprehensive analytical verification.
Q: Do you offer bulk quantities for institutional research?
A: Yes. We accommodate bulk orders for research institutions. Contact our team now for volume pricing, custom requirements, and supply agreements for ongoing research programs.
Advance Your Research with ADAMAX 5mg
peptology.store is your trusted source for ADAMAX 5mg, the premium choice for researchers investigating lipid metabolism, obesity mechanisms, and β3-AR pathway signaling. With over two decades of published research supporting its effects on lipolysis, fat oxidation, and energy regulation, this peptide represents a well-characterized tool for exploring the complex biology of adipose tissue metabolism.
Whether you are exploring lipolysis mechanisms, designing obesity studies, investigating fat oxidation pathways, or researching β-adrenergic receptor signaling, our rigorously tested compound provides the quality and consistency your work demands.
Order today and experience the peptology.store difference – premium quality, rapid 48-hour delivery across the EU and UK, and expert support for the European research community.
